COVID-19 Vaccine mRNA Converts to DNA - PART 1
My brain is spinning. Maybe some readers can help!
An impactful, and scary, peer-reviewed study has just been published.
Before I begin, I want to preface this by saying I am not a geneticist, immunologist, microbiologist, etc. and none of the below has been confirmed in real people. These are findings from petri dish (in vitro) studies, and I have no clue what the real impact of the connections I try to make below are. Maybe they are inconsequential, but they seem very concerning as they run around in my head. Anything I outline below that is not a finding of the cited studies, is all theoretical, but is something that should urgently be investigated! I hope I make that clear as you read.
My Request: If you have any expertise in anything I discuss below, I would love to hear from you in the comments, or via email, to help make sense of this new information.
In Vitro Studies Show Vaccine mRNA and SARS-CoV-2 RNA are Reverse Transcribed into DNA and Possibly Integrated into the Human Genome.
That sure sounds scary!
An in vitro (remember petri dish) study from May 2021 showed that the RNA from SARS-CoV-2 can be reverse transcribed into DNA and be incorporated into the host cell’s DNA. The authors of this paper suggest that this may be one of the reasons for prolonged PCR positive tests in some patients long after symptoms have subsided.
Basically, the cells that got infected with SARS-CoV-2, and had its DNA incorporated into their DNA, may continue to produce what was described as non-infectious portions of the virus for some time after recovery. Since this effect is theorized to continue after symptoms subside, it suggests that not all cells that were infected with SARS-CoV-2 are destroyed by our immune system.
This is not a newly discovered viral phenomenon; it is well known that some virus’s (known as retroviruses) genome is incorporated into host cell DNA.
Now something I think is more concerning, A peer-reviewed study published on February 25, 2022, has shown that the mRNA in the Pfizer COVID-19 vaccine gets reverse transcribed into DNA intracellularly. It does not confirm it enters the nucleus or whether it is integrated into the host cell DNA. However, this theoretically provides evidence that it could be incorporated into the cell’s DNA.
To be clear, the study does not confirm that final step. If the DNA does get into the nucleus but is not incorporated into the host cell DNA it should be dissolved, I believe this is how adenovirus vaccines work.
However, there is something called extra-chromosomal DNA which is DNA contained in the nucleus but not incorporated into the cell’s DNA. The circular form of extra-cellular DNA can be expressed. This has been shown to occur in certain retroviruses, including HIV, and can alter the phenotype (function) of the cell. The following post explains this very well, with citations.
Nevertheless, the above study reveals the possibility that the vaccines could alter Human DNA.
How Does This Happen?
Without going into crazy detail, the reason the researchers say reverse transcription happens is because when the mRNA gets into the cell, it upregulates the production of LINE-1 which is a reverse transcriptase. Reverse transcriptase is an enzyme necessary for the conversion of mRNA into DNA.
NOTE: Some critics of this study point to the fact that they used Huh7 cells. Huh7 cells are an immoral line of human liver cancer cells. This may be an issue with the findings being applicable to non cancer cells. Cancer cells do not have a typical metabolism and some types of cancer cells have increased LINE-1 expression. The study in question did confirm that in the Huh7 cells, the Pfizer vaccine increased LINE-1; however, this does not confirm that the vaccine would increase LINE-1 expression in non-cancer cells. This is an important caveat to consider as we move forward.
Our “officials” said reverse transcription of the vaccine mRNA into DNA was impossible because the vaccines did not contain reverse transcriptase. That statement sure aged well.
Back to the idea of extra-chromosomal DNA. If the vaccine mRNA gets reverse transcribed into DNA and enters the nucleus to form circular extra-chromosomal DNA, this extra-chromosomal DNA can be transcribed to mRNA to create more spike. Additionally, since the noted study shows that the presence of the spike mRNA appears to up regulate LINE-1, the newly transcribed mRNA could very well upregulate LINE-1 like it did when it came directly from the vaccines, leading to reverse transcription to DNA and entry into the nucleus as new circular extra-chromosomal DNA. Therefore, even though extra chromosomal DNA eventually gets degraded, there is a theoretical possibility of a constant loop of transcription, reverse transcription that will continue to produce spike and extra-chromosomal DNA.
So, even if the reverse transcribed DNA does not get integrated into the host DNA, it could still be expressed via extra-chromosomal DNA, and cause problems.
Remember, this is theoretical.
Here is an easy-to-understand video clearly explaining the study.
Natural Infection VS Vaccine
The main reason I said that it is more concerning if the vaccine mRNA gets reverse transcribed and integrated into cellular DNA is because the vaccine is injected and bypasses the mucosal membrane in the respiratory tract.
With natural infections, the virus is only found in the blood of 44% of those on a ventilator, 27% of those hospitalized, and 13% of those treated as outpatients. It is likely much lower for those that do not seek any treatment following infection. Basically, if the virus doesn’t get into the blood, it stays in the respiratory tract and any “genetic altering” would be confined to those tissues.
Alternatively, because the vaccine is injected, it is guaranteed to end up in circulation and travel to many different tissues. Additionally, the alterations made to the vaccine spike mRNA appear to allow it to survive longer in circulation than from natural infection.
How Bad Could This Be?
Now, to figure out how detrimental this could be we have to consider a few things:
The spike protein itself is a toxin.
Does the reverse transcribed mRNA code for anything other than spike, if so, is it possibly dangerous)?
Are all infected (by the vaccine) cells destroyed by the immune system or do some survive?
If they survive, where are they located in the body and, do they replicate?
When and how are the “new” DNA components expressed. Ex. always, sometimes, not at all? AND what proteins do they code for?
Could this impact germ-line cells (sperm/ova) making the DNA alterations heritable?
What about the upregulation of LINE-1 on its own?
The SARS-CoV-2 and mRNA Vaccine Spike Protein is an Established Toxin.
To address the first point: the spike protein itself is a toxin.
It is well known that the SARS-CoV-2 spike protein is a toxin all on its own and may be responsible for some of the symptoms of COVID-19. Since the COVID-19 mRNA vaccines code for the spike protein, it is suggested that this is one of the reasons for the adverse reactions from these vaccines.
Basically, whatever cells the vaccine gets into, it causes them to produce spike protein and express it on the cell surface, I have been told spike protein cleavage is not supposed to occur; however, spike protein is found circulating in exosomes four months after vaccination. Whether this occurs from some type of cleavage or not, the spike protein clearly circulates.
Therefore, if the spike coding DNA from the vaccine gets incorporated into the host cell, and the immune system does not destroy it, it may continue to produce spike protein for an unknown amount of time. Additionally, if the cell is a dividing cell (which is most tissues in the body) all its descendants will also have DNA coding for spike protein. This provides a mechanism for why spike is observed to circulate for up to 4 months.
There Are Possible Issues Even if the Spike Protein Doesn’t Circulate.
The reverse transcription study suggested that autoimmunity may be a concern related to these findings. The vaccines were designed, as I mentioned, to cause cells to produce the spike protein and express it on the surface of the cell. Then, the immune system is expected to recognize the cell as infected and destroy the cell. As a result, our adaptive immune system creates antibodies to spike protein.
Now, let’s say the vaccine gets into a liver cell (the type of cells used in the reverse transcription study), the mRNA is reverse transcribed into DNA and incorporated into the cell’s DNA. The cell somehow evades initial immune system attacks and survives. Liver cells divide very fast, so the cell with the altered DNA produces many descendant cells. However, from adaptive immune reactions to the vaccine in other areas of our body, our immune system is primed to attack cells expressing spike on their surface. See where I’m going?
Theoretically, our immune system could start attacking all the liver cells that are now expressing spike. This would be considered autoimmune hepatitis caused by the vaccine. The researchers specifically identified this as an area for further research considering their findings.
This same theory could be applied to other tissues of the body where cells divide.
Remember this is theoretical, not proven!
Could Spike DNA Lay Dormant?
What if a cell has the vaccine spike coding DNA incorporated into its DNA but the cell does not express it for some reason? Could it lay dormant for an unknown amount of time until some environmental circumstance trigger expression of the spike protein again?
We know viruses such as herpes zoster (chickenpox) lay dormant in nerve cells and can express as shingles decades after initial infection.
Again, just a theoretical question.
OK, this article is getting long , I am sure everyone is bored and terrified all at the same time. I know I am. I’ll post part 2 shortly, there is much to consider.
Time for a drink, or a workout…. probably a drink.
